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Anti-Inflammatory Activity of Silver Nanoparticles Synthesised Using Hing Oil: An In Vitro Study
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| Author:
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DHARAHAAS.C , ANITHA ROY, S. RAJESHKUMAR, DR. LAKSHMI THANGAVELU
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| Abstract:
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Aim: The aim of the study is to determine the antiinflammatory activity of hing oil mediated silver nanoparticles.
Materials and methods: 1mL of hing oil was mixed with 99 mL of distilled water for half an hour. Silver nitrate was added and kept in an orbital shaker with a magnetic stirrer for 2 hours and colour change was observed for 3 days. After this the extract is centrifuged and the silver nanoparticles were obtained. The anti-inflammatory activity of synthesized nanoparticles was analysed using albumin denaturation assay.
Results: The peak found at 650 nm in the UV- Visible spectroscopy indicates the formation of silver nanoparticles. From the study it was found that with the increase in the concentration of the Hing oil mediated silver nanoparticles, The Hing oil mediated silver nanoparticles showed maximum anti-inflammatory activity with 91.5% inhibition at 50 µL.
Conclusion: Silver nanoparticles have good anti-inflammatory activity and can be used in the future as pastes, gels and so on for topical application instead of using conventional anti-inflammatory agents to minimize their side effects.Silver nanoparticles synthesised was eco- friendly, cost effective and wide range of applications.
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| Keyword:
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silver nanoparticles, anti-inflammatory activity, bovine serum albumin
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.422
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| Download:
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