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Anti-Inflammatory Effect Of Herbal Formulation Of Tulasi , Aloe Vera And Turmeric Aqueous Extract
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| Author:
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DHANVANTH.M , UMA MAHESWARI.T.N, S RAJESHKUMAR
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| Abstract:
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Aim: To prepare an in-situ gel containing tulasi, aloe vera and turmeric and plant formulation, and analysis of its anti-inflammatory effects. Tulasi is a medicinal plant that helps in reducing inflammation by inhibiting the inflammation causing enzymes. Turmeric acts as a chemopreventive agent that inhibits the development of oral cancer. Aloe vera is a natural plant and its extract promotes wound healing, and also has anti-inflammatory, immunomodulatory, and antioxidant properties. Turmeric has been found to inhibit many disease processes through their anti-inflammatory, antioxidant and anticancer properties.
Materials and methods: This study extracts are used in preparing in-situ gel. About 1g of tulasi, aloe vera and turmeric was mixed with 100 mL of distilled water and boiled for 15 minutes, these contents are then mixed with anti-inflammatory assay using bovine serum albumin (BSA) to find the anti-inflammatory activity of this plant herbal formulation.
Results: In-situ gel which has more gelation and bioavailability was prepared, anti-inflammatory assay showed significant results with 50 µL (83.8) of gel.
Conclusion: from the above results it can be concluded that the in-situ gel containing tulasi, aloe vera and turmeric have significant anti-inflammatory activity and the advantage of in-situ gel of having higher bioavailability, ease of use and most importantly less systemic side effects.
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| Keyword:
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Tulasi, Aloe vera, Turmeric, anti-inflammatory
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.440
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| Download:
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Request For Article
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