|
In-vitro Free Radical Scavenging, Antibacterial, Cytotoxicity of Ethanolic/Hydroethanolic Extract Of Capparis Decidua
|
|
| Author:
|
PREETHA S, ANITHA ROY, RAJESHKUMAR S
|
| Abstract:
|
Bacckground:
The medicinal plants are being traditionally used due to their strong therapeutic effects, recently owing to their nutritional benefits and their medicinal value The search for non-toxic effective natural compounds rich in antioxidants is warranted in recent years to combat the stress and to fight against diseases. The antibacterial activity is another widely studied activity of the plant as there has been a development of resistant bacterial strains to the most common antibiotics which has been observed in recent years. Capparis decidua is one such very important medicinal plant of our country having its unique place in the treatment of many diseases in conventional system of medicine
Materials and Methods:
The ethanolic and hydroethanolic extract of the plant Capparis decidua fruit is assessed for its antioxidant, antibacterial and cytotoxicity activity. Antibacterial activity is evaluated using agar well diffusion method like Enterococcus faecalis, klebsiella pneumonia, Pseudomonas aeruginosa, Streptococcus mutans, Escherichia coli. Antioxidant activity is evaluated by DPPH free radical scavenging assay. Cytotoxicity activity was evaluated using Brine shrimp Lethality test.
Result and discussion
The ethanolic and hydroethanolic extract of Capparis decidua fruit showed very good antioxidant activity when compared with the control. Both the extract preparations showed a very good antioxidant activity against DPPH at different concentrations. The plant extract was also found to possess good antibacterial activity against most of the bacterial strains studied. The study showed there was very less toxic effect in both the extract of Capparis decidua against Nauplii shrimps.
Conclusion:
The ethanolic and hydroethanolic extract of Capparis decidua thus possess good antioxidant activity and antibacterial activity. The study also showed there was very less toxic effect in both the extract of Capparis decidua. But further investigations are required to study the phytochemicals involved for its activity.
|
| Keyword:
|
Capparis decidua, DPPH radical, Antioxidants, Antibacterial activity, Cytotoxicity, Phytochemicals
|
| EOI:
|
-
|
| DOI:
|
https://doi.org/10.31838/ijpr/2020.SP1.438
|
| Download:
|
Request For Article
|
|
|