*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *       

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
No Data found.
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Intra Nasal Drug Delivery an Alternative Route for Brain Targeting-A Review

Author: NIRANJAN BABU.M, CHANDRASEKAR R
Abstract: Chronic pain syndrome is a severe disorder which includes fibromyalgia, rheumatoid arthritis, cancer related pain and several other pains. Pains are very severe in the age above 60 like rheumatic pains. The prevalence of chronic pain is high in developed and developing countries. There is a significant increase in chronic pain prevalence studies in the world. Chronic pain is severe condition were treatments are offered with NSAID’s, topical formulations, sprays. These medications can offer only a temporary relief. There is no permanent relief for chronic pains. Pain is an immune mediated disorder which leads to sleeplessness, stress, tired. Normally chronic pains cannot be cured by treatment with modern medicines, but they are available with severe toxic effects. Treatments are available with pain relievers which may give a temporary relief but with severe side effects. Treatments with herbal remedies are available with essential oils as a combination of different essential oils which can be used as an oil bath these oils can relieve pain to some extent and can give a relief to patients with chronic pain. Hence when a natural product containing essential oil is selected the compound must contain phytoconstituents which include many secondary metabolites such as alkaloids, glycosides, terpenoids and steroids. The selected compound must be free from side effects and toxicity, should be having better potency and efficacy and safe to use. Nasal sprays are agents which can deliver medicaments directly to the brain by targeting pain receptors in the brain. Nasal sprays are more efficient way of administering drugs with potential use in crossing the blood–brain barrier. This review mainly focuses on intra nasal drug delivery and transport of drugs through the olfactory route and also reviews the recent development in nanotechnology and role of Nanoparticles used in the nose-to-brain drug delivery.
Keyword: Intranasal Drug Delivery, Chronic Pain Syndrome, Essential oil, Nanoparticles
DOI: https://doi.org/10.31838/ijpr/2020.SP2.358
Download: Request For Article
 
Clients

Clients

Clients

Clients

Clients
ONLINE SUBMISSION
USER LOGIN
Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free