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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Spectral Characterization And DNA Binding Properties of Dinuclear Cobalt (II) Complexes 2,4-Dihydroxyacetyl-4-Hydroxybenzoic Hydrazone

Author: , MOHAMMED FADHIL EESEE, M. SUBBA RAO
Abstract: Cobalt is a silver-white, ferromagnetic, hard, lustrous atom which can be magnetized. In this study we synthesized cobalt complexes and DNA binding properties were identified. The observations recorded clearly indicate that 2,4-DHAHB is a potential analytical spectrophotometric reagent. It is seen from the table that the reagent forms coloured complexes with several transition metal ions. Hence, a comprehensive study of zero and first order derivative spectrophotometric determination of some important transition metal ions was undertaken with a view to develop new, simple and rapid procedures for individual and simultaneous determination in mixtures of some transition metal ions of industrial, agricultural and biological importance. Direct spectrophotometric studies relating to the colour reactions between 2,4-DHAHB and cobalt(II) are presented.
Keyword: Cobalt, Hydrazones, 2,4-DHAB, Spectrophotometry, DNA binding
DOI: https://doi.org/10.31838/ijpr/2020.SP2.311
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