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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparative Evaluation of Intraoperative Cytology and Histopathology in Ovarian Neoplasms

Author: , MAATHER BAQER HUSSEIN AL-HARMOOSHEE
Abstract: Neoplasms of the ovaries are a heterogeneous types of benign and malignant neoplasm of versatile origins (epithelial, stromal and germ cell). The clinicopathological evaluation of ovarian masses is a challenging field. Histological assessment of a paraffin section still the gold standard in diagnosis. Single completely reliable method for diagnosis of surgically removed specimens has not yet been developed. Cytology has been underutilized as a modality for the diagnosis of ovarian tumors. With the advent of accurate imaging techniques like ultrasonography (USG) and computed tomography (CT) scan in detecting the ovarian lesions and omental or peritoneal deposit, guided fine needle aspiration cytology (FNAC) has assumed a definite role in diagnosis and management. The use of cytology in intraoperative diagnostic ovarian neoplasms, while commonly used for the intraoperative diagnosis of various tumors, was not widely known. We assumed this research to estimate the accuracy of intraoperative cytology for detection types of ovarian tumors matching to histopathological diagnosis, considered the gold standard. Cytology does not modify the biopsy specimen quality and its materials can be utilized in flow cytometry and cytogenetic studies.
Keyword: intraoperative cytology; Ovarian neoplasms; biopsy.
DOI: https://doi.org/10.31838/ijpr/2020.SP2.330
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