Resveratrol 1,3,4-Thiadiazole Synthesis, Characterization and Biological Study
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Author:
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DHIAA ALI, ASHOUR H. DAWOOD, KARIMA FADHIL
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Abstract:
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The synthesis and characterization of Resveratrol-1,3,4-Thiadiazole derivatives were carried out through the reaction of Resveratrol with ethyl chloro acetate, the result product was react with Hydrazine hydrate to from the hydrazide derivatives, then the CS2 was add to the product to form the diazole. The final product was prepared by react the alkyl halides with the Thiadiazole compounds.
The prepared compounds were characterized by 1H-13C NMR and FT-IR spectroscopies, the physical properties and melting point was measured and the biological activity was study with some common bacteria.
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Keyword:
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Resveratrol, 1,3,4-Thiadiazole; pharmaceutical compounds
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.323
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