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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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“Development of A Pediatric Focused Trigger Tool to Assess the Prevalence of Adverse Events at A Hospital Setting: A Retrospective Structured Chart Review” [PFTT-RSCR]

Author: GEETANJALI S, M S GANACHARI
Abstract: The present study was conducted to develop a paediatric focused trigger tool by retrospective structured chart review [PFTT-RSCR] by modifying ‘Institute for Healthcare Improvement’s Global Trigger Tool’ [IHI-GTT] adult version. It is useful for the effective assessment of adverse event prevalence in hospitalised children at a tertiary care set-up. The trigger tool was developed in the paediatric population in two stages using literature search by Delphi panel review, consisting of Clinical Pharmacy researcher and/or reviewers (PRR’s-Reviewer panel I & II) and physician as peer reviewer (PPR’s-Reviewer panel III). Triggers were added or deleted with respect to positive predictive value of a trigger towards the development of tool for the assessment of adverse events upon consensus of reviewers. Among 2500 patient charts screened, Out of 520 randomly selected sample, 352 completed charts were reviewed retrospectively. AE’S were found to be 124 with 437 Triggers with Positive Predictive Value (PPV) of 28 % in the final trigger list of 40 in 05 modules, 81 were with 1 adverse event and 35 were with more than one. Sixty-six of (66) the patients records (23.23%) had at least 1 adverse event during their hospitalization, and at least 26 (9.15%) had more than 1 event Pediatric-Focused Trigger Tool (PFTT) with well-defined triggers by expert review from clinical and research area along with broader literature review, will help to assess the adverse events in a more reliable manner upon validation in the Indian health set-up.
Keyword: Adverse events, Review panel, Pediatric-Focused Trigger Tool, Positive Predictive Value
DOI: https://doi.org/10.31838/ijpr/2020.SP2.160
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