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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Competence of Nerium oleander oil against Sarcoptes scabiei in vitro

Author: , MSC.NOOR M. HASNAWI, DR.SHAIMAA A. SHLASH
Abstract: This study aimed at understanding the capability of essential oil leaves extracts of Nerium oleander on Sarcoptes scabiei in vitro, which were done during the period from September 2019 to February 2020. In the current study, 125 female patients infected with scabies were examined, the mites were isolated in petri dishes with four various concentrations (3, 9, 18 and 36 mg/ml) after 72 h of contact with 36 mg / ml concentration of Nerium oleander oil exhibited mortality 100% mite in vitro acaricidal affected correlated with the untreated control (p<0.05). The lethal concentration values were resolved after 24 h of exposure by N.oleander oil extract versus the larvae and adult Sarcoptes scabiei has been LC50 was 13.99 mg/mL while relative toxicity was 100%. These results point out that N.oleander oil have capacity acaricidal activated in vitro and may control the mites in human and animals.
Keyword: Nerium oleander, Oil extract, Mite, Sarcoptes scabiei.
DOI: https://doi.org/10.31838/ijpr/2020.SP2.144
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