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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Biochemical Study of Leptin and Associated with Hypertension Patients in Iraq

Author: ASSALA SALAM.J, PROF. DR. MOHAMMED A. AUDA, PROF. DR. DHYAA KHALAF
Abstract: This study was conducted to find out the effect of high blood pressure on some biochemical variables in the blood, and compared them with normal values (control groups) of (45) (23 females and 22 males) whose ages ranged between (49-70 years) and )Patients group( Includes (45) persons(16 females and 29 males) with high blood pressure, ages (45-75),the study included the following variables Leptinhormone , Cho, TG, HDL, LDL, VLDL. The results of the study showed a significant increase (=p05.0) in the concentration of cholesterol, triglycerides, low lipoprotein, and very low density lipoprotein compared with the control group, but the high density lipoprotein showed a significant decrease (=p05.0) compared to the control group. As for the results of the hormone leptin, the study showed that there was a significant increase in the concentration of the hormone in hypertensive patients compared with healthy subjects. When calculating the linear correlation coefficient to clarify the relationship between the chemical variables, it was found that there is a significant direct correlation (between cholesterol and triglycerides and the hormone leptin) and there was a significant direct correlation between the hormone leptin and both (triglycerides and low density lipoprotein with high density lipoprotein).
Keyword: Leptin; hormone ; Hypertension ;Cho;TG; HDL; LDL; VLDL.
DOI: https://doi.org/10.31838/ijpr/2020.SP2.149
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