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Evaluation of antiepileptic medication adherence among paediatric epileptic patients: a randomized prospective study in a teaching hospital
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| Author:
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SHASHIKALA WALI, NIRANJANA MAHANTSHETTI, M S GANACHARI, ASHISH P, RAMESH BHANDARI
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| Abstract:
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Background: Epilepsy is a Neuro-degenerative disorder characterized predominantly by recurrent and unpredictable seizures and discharges from the cortical cells of the brain. Long term therapy is required for treatment of epilepsy. The non-adherence is the serious concerned in cases of all patients.
Objectives: To compare and assess the medication adherence of antiepileptic drugs on paediatric patients at different point interval.
Methodology: The prospective, randomized study has been conducted in out-patient department of Paediatric at tertiary care hospital of Belagavi district, Karnataka, for 12 months including 1 follow-up of 6 month interval. The patients newly diagnosed with epilepsy of either sex aged between 1 to 18 years with signed with assent and consent were collected.
Result: 103 epileptic patients were screened for the study. In that, 65 patients were found to fit for study criteria. Randomized into 2 groups control n= 24 and Intervention = 41. There was no significant difference (p=0.903) observed in gender distribution among both groups, similar findings p=0.116 was found in age distribution. Medication adherence observed among both the groups at baseline level were no significant difference (p=0.718) was observed in control group (6.92±1.01) and in interventional group (6.78±1.03), highly significant improvement p= 0.0001*** observed in interventional group (3.61±1.49) instead of control group (5.38±1.23).
Conclusion: Clinical pharmacist assists in recommended antiepileptic medication use process by counselling which will increase medication adherence, reduces risk of seizure and enhance quality of life.
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| Keyword:
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Medication Adherence, Paediatrics, Anti-epileptic agents, Epilepsy, Clinical Pharmacist, Pharmaceutical care.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.118
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| Download:
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