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Conjunctival Bacterial Flora And Their Antibiogram: A Study On The Patients Attending National Medical College & Teaching Hospital Of Birgunj, Nepal
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| Author:
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DIPAK BHARGAVA, SUMAN KUMAR HALDER, SANJAY KAR, PADAM RAJ BISTA
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| Abstract:
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Aim: Assessment of clinical symptoms followed by microbiological analysis and antibiogram profiling are obligatory for prompt treatment of bacterial conjunctivitis. In this study effort has been made to evaluate the microbiological profile of bacteria causing conjunctivitis along with clinical symptoms and their antibiotic sensitivity pattern in Birgunj adjoining area, Nepal.
Materials and Methods: Clinical information and conjunctival swabs were collected from 260 patients and processed as per standard bacteriological methods. Data were statistically analyzed using one-way ANOVA in Sigma plot 11.0 (USA) to determine the significant difference between the means.
Results: The incidence of bacterial conjunctivitis was found to be maximum among <10 years age group (28%) with an overall male preponderance of 62%. More than 60% of the patients have running nose (65%) followed by profuse discharge from the ocular area (52%). The commonest bacterial causative agent was Staphylococcus aureus (46%) followed by Streptococcus spp. (17%) and coagulase negative Staphylococcus spp. (12%). Among the gram negative isolates, Pseudomonas spp. are predominant (9%). Antimicrobial profiling revealed that S. aureus shows higher degree of resistance against erythromycin, chloramphenicol and cotrimoxazole. The most effective antibiotics against the isolated bacterial antibiotics were cloxacillin, amoxicillin/clavulinc acid and ceftriaxone.
Conclusion: The knowledge of antibiogram for bacterial conjunctivitis is a prerequisite for the proper treatment and control of the infection. Systemic large scale studies should be conducted for regular monitoring of the antibiotic susceptibility pattern which might help in reducing the resistance of the commonly used drugs used against bacterial pathogens.
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| Keyword:
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Bacterial conjunctivitis, Antibiotic susceptibility test, Staphylococus aureus, Bacteriological analysis
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.369
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| Download:
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