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Assessment of drug therapy problems and drug utilization pattern in stroke patients
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| Author:
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A.PRIYADHARSHINI , ANIRUDH.M, FATEMAJUZER HAJI, AHALYA S.P
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| Abstract:
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Stroke is the third leading cause of death after heart diseases and cancer. Drug therapy is more complex nowadays; where inadequate and irrational prescriptions could lead to serious consequences. Polypharmacy is unavoidable in the stroke as the patient suffers from multiple co-morbidities, which may lead to many drug related problems. Objective: The present study was aimed to evaluate the drug use pattern and drug related problems in stroke patients. Methods: A Prospective Observational study conducted for 8monthsat a tertiary care teaching hospital Results: Among 100 patients 76% males and 24% females were found with stroke. Around 93% was diagnosed with ischemic stroke and 7% with haemorrhagic stroke. The average number of drugs per prescription is 8.6. The most used drug were Anti-hypertensives 13.60%, Anti-platelets 9.42%, Neuroprotectives 8.96% and Dyslipidemic agents 7.45%. A total of 8.02% high alert medications were prescribed in 100 stroke patients. DDI is the most common drug related problem. 94 prescriptions were found with minimum of 1 drug-drug interaction. 11% of patients were reported with an ADR. The rationality of the prescription among geriatric patients were analysed according to beers criteria. Results stated that 63.3% prescriptions are found to be irrational in geriatric population.Conclusion: The drugs that are majorly prescribed in stroke were antihypertensive, neuroprotectives, antiplatelets and dyslipidemic agents. Drug related problems in may lead to increased risk of hospitalization and higher health care cost. The physician should be aware of these problems while prescribing for stroke patients, in geriatrics and thorough monitoring should be done for patients’ safety.
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| Keyword:
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Stroke, DUE, DRPs, Rationality of prescription
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.323
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| Download:
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