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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Development Of Technology And Composition Of Alhagi Kirghisorum Schrenk (Camel Thorn) Extracts Based Tablets

Author: TEMIRBAYEVA K.B, USTENOVA G.O, AMIRKHANOVA A.SH, RAKHIMOV K.D, KAUKHOVA I.E, TURGUMBAYEVA A.A, ZHAKIPBEKOV K.S, SHYNYKUL ZH.SH
Abstract: The object of this study is dry camel thorn extract (Alhagi Kirghisorum Schrenk). When analyzing internet sources, materials on the camel thorn were collected and we studied its types. The technological properties of the substance - dry camel thorn extract (Alhagi Kirghisorum Schrenk), obtained under supercritical conditions, have been studied. The purpose of the study was to develop the composition and technology of producing tablets based on camel thorn extract: the effect of alcohol concentration on the process of wet granulation of a mixture of powders containing a dry extract. Ethyl alcohol at a concentration of 30% was chosen as the granulating liquid. The granulate is a free-flowing powder of a light brown color, convenient for the tabletting process, and we developed the composition of the tablet mass and the technology of tablets based on a dry camel spine extract. A composition was selected and a film coating technology was developed based on Vivacoat formulations. Tablets were obtained round, biconvex, diameter 12 mm, color light green with pearlescent. According to the pharmaceutical indicators, tablets of the selected composition comply with the requirements of the State Pharmacopoeia of the Republic of Kazakhstan.
Keyword: Alhagi Adans, Alhagi Kirghisorum Schrenk, traditional medicine, dosage form, tablet.
DOI: https://doi.org/10.31838/ijpr/2020.SP1.311
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