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Antidiabetic Phytochemicals: A comprehensive Review on Opportunities and Challenges in Targeted Therapy for Herbal Drug Development
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| Author:
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P.PRABHAKAR , MAMONI BANERJEE
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| Abstract:
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The traditional system of medicine has shown much better improvement, less side effect, and less expensive as compared to modern synthetic drugs in the treatment of diabetes mellitus. Medicinal plants and phytochemicals have much importance in the present scenario in developing countries where resources are limited. The effectiveness and activity of a phytochemical depend upon its binding ability with the target molecules. Identification of the target molecule, its mechanism, and interaction with the specific phytochemical drug, can be proved to be an efficient therapeutic against diabetes. This review addressed different classes of molecules and enzymes involved in the pathogenesis of diabetes mellitus, antidiabetic activities of different classes of phytochemicals, its activity on antidiabetic drug targets, as well as possibilities of herbal drug development for diabetes in context with targeted therapy.
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| Keyword:
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Diabetes, synthetic drugs, side effects, herbal drugs, Phytochemicals, target molecules
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.242
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| Download:
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