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Effect of Harmonic Scalpel and Nano-Magnesium Oxide on Lung Lobectomy Healing In Dogs: Macroscopic and Microscopic Study
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| Author:
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O.A.BADER , M.J.EESA
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| Abstract:
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The objective of this study was to evaluate the role of harmonic scalpel in middle lobe of right lung lobectomy thoracoscopically and the effect of nano magnesium oxide on the healing of lung tissue at lobectomy site. Twenty-four adult local breed dogs were used. They were divided randomly into two equal groups (control and treated group). Under inhalation anesthesia using halothane with positive pressure ventilator and aseptic surgical technique, the middle lobe of right lung was resected via harmonic scalpel in addition to that using titanium clips to control bleeding and air bubble leakage. Macroscopic and microscopic examination at three and five weeks post operation were evaluated. Macroscopic findings thoracoscopically were revealed that all animals in control group had adhesions in different degrees of evaluations and in different sites, while in treated group showed no adhesion at the surgical site. In treated group the histopathological examination at 3 and 5 weeks post operation shows normal lung architecture through presence of pneumocytes type I lining the alveoli especially at 5 week post operation and disappeared of inflammatory pictures, while in control group the presence of mature granulation tissue, collagen fiber and thickening of bronchial wall was noticed at the end of 5 weeks post operation.
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| Keyword:
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Thoracoscope, Harmonic scalpel, Nano magnesium oxide, Lung, Dog.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.253
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| Download:
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