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Quantitative Determination of Sulfamethoxazole and Trimethoprim Via-Ratio Spectrum Derivative Method in Combined Pharmaceutical Mixture
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| Author:
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SHAYMAA ABDUL-RAZZAQ HUSSEIN, EMAN THIAB AL-SAMARRA
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| Abstract:
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Two recent spectra photometric approach were sophisticated for the at same time assessment of SMX together with TMP utilize 'the first proportion derivative DD1 and the second ratio derivative DD2' method. The two manner were succeeded in appreciation of both drugs with a range of concentricities from ‘10 - 45 µg. ml -1’, building on climax to baseline, climax area, climax to climax at particular wavelengths for every 'compound'. The analytic outcome and of the appreciation of the SMX together with TMP appeared such Rec % values ranged from 96.85 – 104.81 %, and 95.26 – 104.92 ;and RSD % were betwixt 0 - 4.73286 % and 0 - 4.22759 % for the 'first and second ratio derivative respectively'. The manner has been successfully applied to the appreciation of both TMP together with SMX in its pharmaceutical form.
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| Keyword:
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Ratio spectrum derivative, sulfamethoxazole, trimethoprim
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.252
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| Download:
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Request For Article
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