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Serum Levels of Cancer Antigen 15.3 and Estrogen in a Samples of Iraqi Women with Breast Cancer Treated with Anastrazole.
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| Author:
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SARAH NAJM ABED, HIBA SALAH MAHDI, AHMED SALIH SAHIB, HASSAN MAHMOOD MOUSA ABO ALMAALI, MUDER AL HAYDAR, KARRAR KADHIM MOHSIN
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| Abstract:
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Background: Breast cancer is one of the most frequent cancer in the world. Anastrazole is an aromatase inhibitor which used for treating females with breast cancer by decreasing the level of estrogen.
Aim of study: To study the effect of anastrazole on serum levels of estradiol and tumor marker CA15.3 in Iraqi breast cancer females recruited from oncology center at Imam AL-Hussein Medical city.
Method: The study included 85 females with breast cancer treated with anastrazole. Estrogen (E2) and tumor marker cancer antigen (CA) 15-3 level was measured by already made kits.
Result: The serum CA 15.3 concentrations are within the normal range in about 88.23%, while the remaining are above the normal limit. In case of serum estrogen levels, all patients are within the normal value.
Conclusion: The Serum levels of CA 15.3 in most women treated with anastrazole are within the normal value with only small percentage are above the normal limit. But at the same time the serum estrogen levels are within the normal range in all females.
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| Keyword:
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breast cancer, anastrazole, estradiol, cancer antigen 15.3
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.246
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| Download:
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