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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Synthesis and characterization of some new chalcones derivatives from 3- Acetyl benzocoumarin and studied their anti-cancer activity

Author: NABEEL A.ABDUL–RIDA, AFRAAH D. SALMAAN
Abstract: This study involve synthesis of some new chalcones from 3-Acetyl benzocoumarin as starting material which is reacted with appropriate substituted aldehydes to give the corresponding chalcones, The reaction has been carried out by Claisen-Shmidt condensation in presence of Pipredine as catalysis and Ethanol as a solvent. All Chalcones characterization by FT-IR,13C-NMR, 1H-NMR. Than we studied the anti-cancer activity of some Chalcones.
Keyword: Benzocoumarin, Chalcones, Anti-cancer.
DOI: https://doi.org/10.31838/ijpr/2020.SP1.236
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