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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Estimation the level of CA-125 and Alpha-fetoprotein AFP in sera of Iraqi women ovarian cancer

Author: ZAHRAA NEAMAH ABBAS, GHASSAN ABDULLA RADDAM
Abstract: This research is conducted to make an obvious integrative thought on the effect of expression of CA-125 and a-feto protein in ovarian cancer among Iraqi women patients confront with unaffected Iraqi women. Two studied groups include (60). Ovarian cancer women and 20 healthy controls Using ELISA method for evaluation quantitatively for CA-125 & a-feto protein. This research statically exhibited elevated level of CA-125 throughout effected group(74.00±8.723) in comparison with healthy control group (20.05±1.515).On the contrary highly considerable variation between them (P>0.01).on the other hand a-fetoprotein also showed big variation between patients groups (7.853±3.987) and control groups (4.270±1.4800) (P>0.01). Analysis of our datum display a tendency to increase with age stratum (40-49) years was found to be highly frequent in both studied groups (patients and control groups) with no considerable variation between them (P>0.05). The conclusion of this study indicated that CA125 & a-feto protein are very important clinical markers for the detection and management of ovarian cancer.
Keyword: Ovarian cancer, CA-125, Alpha-fetoprotein, ELISA
DOI: https://doi.org/10.31838/ijpr/2020.SP1.230
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