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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparisions of the severity of psoriasis with metabolic comorbidities in kanchipuram district

Author: ANJUMEENA D, MARIA ANNITA TELLCOTT
Abstract: Severe psoriasis has a 50% improved risk of mortality that outcomes in death within 50 years. Obesity per se is a risk factor for emergent psoriasis in about 30% of patients. All these metabolic disorders may lead to worsening of severity of psoriasis. Given the suggestionamong psoriasis and metabolic syndrome, it is important to screen all the patients with psoriasis as part of routine medical care and thereby take measures at lowering cardiovascular risk at the earliest.The objective of my study was to evaluate the clinical and laboratory parameters associated with metabolic co morbidities and their relationship with Psoriasis.Factors causing disparity in Variation of the prevalence of psoriasis include age, gender, geomorphology, and ethnicity, genetic and environmental factors. Higher incidence fees were located at better latitudes and in Caucasians in contrast with other ethnic businesses.Informed consent was obtained from all the patients, history of duration of psoriasis, past history, family history and treatment history were noted down. Height and weight were measured and BMI was calculated. Waist circumference was measured. Blood pressure was recorded. The blood investigations and electrocardiogram were also taken.The total number of patients in my study was 106.Out of which 56.6% had association with metabolic syndrome and 30.2% had ECG abnormalities. Both genders were equally affected. Most of the patients (32%) were between the age group of 58 to 67 years. The duration of psoriasis ranged from 1 month to 15 years. The mean (± standard deviation) duration of psoriasis was 5.9 years (±3.8 years) Psoriasis vulgaris was the most common type 81.1% out of which severe psoriasis was seen in most of the patients (39.6%).Nail changes were seen in 49.1%. Allowing to NCEP ATP III criteria, metabolic syndrome was present in more than half of the patients (56.6%).
Keyword: ATP III (Adult treatment Panel),National Cholesterol Education Program,metabolic syndrome,BMI,blood investigations and electrocardiogram
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