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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Neurological Complications Of Extremely Low Birth Weight According To The Data Of Belgorod Region

Author: IGOR I. DYUMIN, ELENA A. BALAKIREVA, ELENA V. PODSVIROVA, VALENTINA S. POPOVA, IGOR V. NIKOLAENKO
Abstract: The central nervous system damages in newborns dominate among the causes of early morbidity, disability, and mortality. The most severe disabling brain damages in newborns are intraventricular hemorrhage, which occurs in 60-90% of premature infants. Objective: A comparative analysis of the frequency and severity of IVH in children with extremely low body mass. Methods: Case histories of 314 newborns, 264 children with extremely low body weight and 50 children with very low body weight, who represented the control group, were studied. Results: Severe hemorrhages (III-IV degree) clearly prevailed in the group of deceased children with ELBW. Comparison with Student t-test showed a statistically significant difference between the main and control groups (p <0.05) due to the group of deceased children with ELBW. Conclusion: The analysis showed a high prevalence of IVH of varying severity in very premature infants - more than 60% of cases. Statistical significance (p <0.05) was established for the group of children with ELBW who died in the first stage of nursing compared with the survived with ELBW and the control group according to the criterion of severity of IVH. Based on the obtained data, the presence of severe IVH in premature infants with ELBW can be considered a prognostically unfavorable survival factor.
Keyword: premature newborns, extremely low birth weight (ELBW), intraventricular hemorrhage (IVH).
DOI: https://doi.org/10.31838/ijpr/2020.SP1.152
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