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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Diagnostic Criteria of Seronegative Spondyloarthritis: Stages of Development and Optimization (Comparative Analyses)

Author: KHAIDAROVA YU.M., KURMANOVA G.M., SEIZHANOVA B., NURGALIEVA G.K., ZHETPYSBAI A., TOKTARBAI S., KURMANBEKOVA M.B., YESSIRKEPOVA G.S., BEISEBAYEVA A.K., MOMINOVA G.N.
Abstract: Seronegative spondyloarthritis (SPA) is a group of chronic inflammatory rheumatic diseases characterized by a common clinical and radiological picture, early diagnosis, which still remains a problem for rheumatologists and general practitioners. Over the past decade, fundamental changes have occurred in early diagnosis through the evolution and optimization of diagnostic criteria. For example, the proposed diagnostic criteria for axial spondylitis are based on only two diagnostic components: the presence of a genetic marker - HLA-B27 or sacroiliitis, confirmed by magnetic resonance imaging or radiography. Before evaluating the effectiveness and functionality of all diagnostic criteria in comparison with the ASAS criteria (2009, 2011), we would like to study in detail the history of the emergence and optimization of classification criteria as new data are collected. This work allows us to analyze the strengths and weaknesses of the diagnostic criteria, evaluate and compare them with each other and further understand the need to develop new criteria for the early diagnosis of SPA in the epidemic zone for brucellosis and the effective work of doctors.
Keyword: seronegative spondyloarthritis, ankylosing spondylitis (AS), difference in diagnostic criteria, Modified New York criteria, ASAS.
DOI: https://doi.org/10.31838/ijpr/2020.SP1.149
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