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A Clinical Study of Psoriasis and its Association With Metabolic Comorbidities
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| Author:
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ANJUMEENA. D, SUNDARAMORTHY SRINIVASAN
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| Abstract:
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Psoriasis is a chronic inflammatory disease connected with comorbidities such as dyslipidaemia, central obesity,
hypertension and glucose intolerance. This study was done to assess the clinical and laboratory parameters
associated with psoriasis.Patients diagnosed with psoriasis and those fulfilling the inclusion criteria were chosen.
Conversantagreement was acquired from all the patients, history of duration of psoriasis, past history, family
history and treatment history were noted down. Height and weight were unrushed and BMI was intended. Waist
perimeter was unhurried. Blood pressure was recorded. The blood investigations and electrocardiogram were also
taken.The total number of patients in my study was 106.Out of which 56.6% had association with metabolic
syndrome and 30.2% had ECG abnormalities. Both genders were equally affected. Most of the patients (32%) were
between the age group of 58 to 67 years. The duration of psoriasis ranged from 1 month to 15 years. The mean (±
standard deviation) duration of psoriasis was 5.9 years (±3.8 years) Psoriasis vulgaris was the most common type
81.1% out of which severe psoriasis was seen in most of the patients (39.6%).Nail changes were seen in 49.1%.
Rendering to NCEP ATP III criteria, metabolic syndrome was present in more than half of the patients (56.6%).
The individual metabolic comorbidities such as blood sugar and cholesterol levels augmented with the harshness of
psoriasis. Hence patients with psoriasis are at augmented risk of emerging metabolic abnormalities and thereby
leading to adverse cardiac outcomes. Hence patients with psoriasis should be routinely separated for the
attendance of comorbidities as part of routine medical care.
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| Keyword:
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Psoriasis vulgaris,Electrocardiogram,Albumin,dyslipidaemia, central obesity, hypertension and glucose intolerance
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| EOI:
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| DOI:
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