|
A review of clinical uses of Bromelain and concerned purification methods to obtain its pharmacological effects efficiently
|
|
| Author:
|
PAROMA AREFIN, MD SHEHAN HABIB, AISHAWARYA AREFIN, MD SAIDUL AREFIN
|
| Abstract:
|
Bromelain comprises a group of proteolytic enzymes obtained from the tissue of Pineapple, Ananas comosus, belonging to the Bromeliaceae plant family. Different studies indicated its antithrombotic, fibrinolytic, antimicrobial, anticancer, and anti-inflammatory properties. Bromelain has significant applications in clinical, industrial, and cosmetic sectors. Therefore, researchers have always explored suitable extraction and purification methods for the final application. In this paper, we have mainly focused on the potential pharmacological activity of bromelain and future applications. We have identified, compared, and evaluated the different extraction and purification methods of bromelain for utilizing its pharmacological activities. We have also discussed the pharmacokinetics, toxicity profile, and health effects of bromelain. The study concluded with findings of a huge area of their clinical uses and proper methods to obtain the purest form of bromelain.
|
| Keyword:
|
Ananas comosus, Anti-Inflammatory Effect, Clinical use of Bromelain, Extraction, Pineapple, Purification
|
| EOI:
|
-
|
| DOI:
|
https://doi.org/10.31838/ijpr/2020.SP1.066
|
| Download:
|
Request For Article
|
|
|