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Extensive Fixed Drug Eruption Due To Furosemide: A Case Report
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| Author:
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MIN BAHADUR LUHAR, S ANUSHA, BASSY K. ALIAS, HN GIRISH, KALA BAHADUR RAWAL, A. ASHVIL
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| Abstract:
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Introduction: Fixed Drug Eruption (FDE) is a common manifestation of hypersensitivity reactions. These are distinctive in nature and can be characterized by the circular lesion of hyperpigmented plaques.
Case report: A 40 yrs old male developed fixed drug eruptions in limbs, lips, trunk, chest, and scrotum after receiving four doses of intravenous furosemide to cure pedal edema. After administration of furosemide, the next day patient developed pigmentation on the leg, irritation, and redness of the eye started pigmentation from legs. It spread to lips, hands, trunk, scrotum, and lower abdomen and diagnosed as FDE by treating physicians. The furosemide was discontinued, and the patient was administered with steroids. The Naranjo’s and WHO causality assessment scale showed the ADR as “Probable and Hartwig and Siegel assessment scales confirmed the ADR as Level 4a” severity.
Conclusion: After the diagnosis was made, furosemide was withdrawn, and the other therapy was unchanged, and symptoms were subsided gradually over a week. The patient got discharged with strict advice for avoiding furosemide in the future.
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| Keyword:
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Adverse drug reaction, Causality assessment, Cutaneous eruption, Diuretics, Naranjo Scale, WHO Scale
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.062
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| Download:
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