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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Synthesis of some new thiazolidinones derivative from progesterones

Author: , HANAA SALEM SHAMKHI, MAHMOOD S. MAGTOOF
Abstract: This study is concerned with the synthesis and characterization of 4-thiazolidinone derivatives (3a,3b). These compounds were prepared by reacting thioglycolic acid with the appropriate Schiff bases (imines) by heating at 50-60 °C in chloroform with moderate yields (51–75 %). The structures of these 4-thiazolidinone derivatives were established on the basis of spectral studies using IR, 1H-NMR, 13C-NMR.
Keyword: Imines, NMR spectroscopy, Synthesis, Thiazolidinones.
DOI: https://doi.org/10.31838/ijpr/2020.SP3.113
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