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Role IL6,IL8,Hu MIF, NF-?B-P65 in the development of trichomoniasis
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| Author:
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, NADIA JAFFER KADHUM, SHAYMAA JABBAR RAISAN, SABEEH H. AL-MAYAH
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| Abstract:
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The present study aimed to assess level of IL6,IL8,Hu MIF, NF-?B-P65 in the serum of women . Collected 80 sample women suffered from vaginal infections, as well as samples were from 10 healthy women as a control group. Results showed a significant increase (P <0.05) in the immunological parameters in the women who were infected with Trichomoniasis parasite versus the women who were suspected and the control group ,there was an increase in the level of IL-6 in the infected women with a concentration rate of 16.19 pg / ml compared to its concentration in the control and suspected women groups and whom their concentration rates were 2.20 and 2.83 pg / ml respectively. When comparing the IL-8 concentration among women infected with T. vaginalis its concentration rate was 9.024 pg / ml, while the concentration rates in the other two groups were 4.306 and 1.957 pg / ml respectively. the concentration of Hu MIF was higher in women infected with T. vaginalis and those who were suspected of being infected , reaching 7.229 and 7.169 ng / ml respectively, compared with its low concentration in women in the control group where it was 1.468 ng / ml. Finally, the highest rate of the NF-P65 concentration was recorded at 2.982 ng / ml in the infected women compared to control and suspected groups, as the concentration rates in these two groups were 2.681 and 2.701 ng / mL, respectively.
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| Keyword:
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NF-?B-P65, Hu MIF, Trichomoniasis, ELISA, Immune
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.571
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| Download:
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