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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Adherence to Anti-retroviral Therapy and Its associated Factors among Patients with HIV/AIDS in Central Java Indonesia

Author: EKA FEBRIYANTI, ZAKKY CHOLISOH , ERINDYAH RETNO WIKANTYASNING, GUYUP SAGOTRA, IKLIL HABIBI MIJIL ANGGORO, CHINTHIA DEVIENTASARI , ENUR NURAENI
Abstract: Purpose: This study aimed to determine the level of adherence and factors enabling a high adherence behavior among patients with HIV/AIDS. Methodology: A cross sectional study was conducted to 130 adult patients with HIV/AIDS who received antiretroviral therapy for at least a month. Patients who were willing to participate were interviewed. Data was analyzed using chi-square test (p<0.05). Results: Overall = 95% adherence of the last month was 72,6%. Adherence was associated with male gender (p=0,042), lower duration of therapy (p=0,042), no smoking habits (p= 0,016) and the distances to health facilities (p=0,004). Multivariate analysis show that distances to health facilities are the most influential factor on the ART medication adherence (p = 0.007) with OR = 5.651.Young age, high level of education, spouse (marital status), good financial status, taking alcohol habits, health insurance coverage, not experiencing adverse drug reactions, and support from family, spouse or friend were not associated with high adherence to ARV therapy. Applications/Originality/Value: Identifying the enablers of high adherence to anti-retroviral treatment can increase the likelihood of anti-retroviral related goal which in turn will reduce the disease related progression and death.
Keyword: anti-retroviral, adherence, enablers, HIV/AIDS.
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