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Aspartate Aminotransferase/ Platelets Ratio Index in Detection of Liver Cirrhosis in Patients with Chronic Hepatitis B Virus
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| Author:
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THURAYA AAMER HABEEB, , THANAA ISMAEL JAWAD(LECTURER), NOOR ISMAEL NASER( PROF. ASSIST), MASAR JABBAR JARY (LECTURER)
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| Abstract:
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Background: Liver cirrhosis is one of most horrible difficulty of incessant hepatitis B infection (HBV) disease. Biopsy is viewed as the highest quality level for conclusion of liver cirrhosis. In any case, this strategy has numerous restrictions.
Aims: to assess the productivity of APRI in discovery of liver cirrhosis in patients with HBV disease.
Subjects and Methods: This case control study included 68 patients with liver cirrhosis just as 50 age and sex-coordinated clearly solid subjects. Serum aspartate aminotransferase and platelets tally were performed for every member, and the aspartate aminotransferase: platelet proportion file: platelet proportion file (APRI) was determined. Beneficiary working trademark (ROC) bend was used to discover the region under-the-bend (AUC) just as the particularity and affectability of APRI in discovery of liver cirrhosis.
Results: The mean APRI score of the patients and control were 1.6±0.62 and 0.25±0.18 separately with a profoundly huge contrast. The AUC was 0.842, p<0.001, CI=0.732-0.953. At cut off an incentive for APRI= 0.65, the affectability and explicitness of the test were 89% and 87% separately demonstrating generally excellent discriminative worth.
Conclusions: APRI can be a solid, straightforward, non-obtrusive, plausible examine for discovery of cirrhosis in patients with HBV, and live biopsy should never again be viewed as mandatory.
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| Keyword:
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Liver cirrhosis, aspartate aminotransferase: platelet ratio index
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.505
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| Download:
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