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Effect of IL-10 and related lead in workers fuel stations in Thi-Qar province.
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| Author:
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SALAH FAIZ SHNAA, MAJIDA G.MAGTOOPH
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| Abstract:
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Benzene has toxic effects on different body systems, the hematopoietic system and immune system are among the affected systems. This study aims to investigate the effect of benzene exposure on some blood parameters of workers at several fuel stations in Thi-Qar province, as well as to reveal if the continuous exposure may induce an inflammatory response, which is reflected by changes in immune system. The study included two groups of males. The first group consists of 60 exposed workers at fuel stations in different locations in Thi-Qar province. The other group is the control group, which consists of 30 non exposed subjects, during the period from (December 2019 to May 2020) .
Methods. Hematological parameters (white blood cells and differential white blood cells) have been evaluated using a Whole Blood Analyzer Coulter (Emerald / Germany) . Serum level of Interleukin-10 ( IL-10) were estimated in all workers and non-exposed using enzyme-linked immunosorbent assay (ELISA). The estimation of Lead (Pb) Concentration in blood by Flame Atomic Absorption Spectrometer (FAAS) of the workers and control groups.
Results. Data showed the higher concentration of Pb in the age groups of workers and duration time groups also significant changes in some parameters with pb in the exposed workers, there was decline but non significant in WBC count and significant change in some types of WBC including , monocytes, and granulocytes , interleukin-10 were significantly changes with pb in exposed workers than in non exposed , with two groups age and time work .
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| Keyword:
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IL-10 , Lead , benzene toxicity
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.504
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| Download:
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Request For Article
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