|
Study on prescribing pattern of antibiotics in surgical prophylaxis
|
|
| Author:
|
AK ASWATHY, NEETHAL SEQUEIRA, SAMUEL GIDEON GEORGE P
|
| Abstract:
|
Background: Surgical Site Infection (SSI) is a common cause of morbidity and mortality and has a negative
impact on the patient's quality of life. Surgical prophylaxis refers to a short course of antibiotics given prior to
surgery. Inappropriate antimicrobial use results in the incidence of drug resistance, toxicity, and prolonged
hospitalization.
Objective: To study the pattern of prophylactic antimicrobial use in surgical patients and to assess the
appropriateness with respect to selection, dose, timing, and re-dosing of antibiotics.
Methodology: A prospective cross-sectional study was carried out for a 6-month time period in a tertiary
care teaching hospital. 110 patients have been enrolled in our research and information regarding the
demographic data, surgery and antibiotic therapy (selection of antibiotic, dose, timing, re-dosing) were
documented.
Results: Of the total 110 patients who received antimicrobial prophylaxis, third-generation cephalosporins
were the commonly used pre-operative antibiotic through the intravenous route. Ceftriaxone (91.03%) was
the commonly prescribed antibiotic in general surgery and orthopedics whereas cefotaxime (84.3%) was the
drug of choice in the obstetrics and gynecology department. The antimicrobials were administered in the
appropriate doses one hour prior to surgery. No intra-operative re-dosing was given.
Conclusion: From the study, the selection of prophylactic antibiotic shows considerable variations. The main
aspect is the unnecessary use of third-generation cephalosporins in a majority of the surgical cases. Thus
practitioners must prescribe an antibiotic based on their hospital antibiotic policy or standard guidelines.
|
| Keyword:
|
Surgical Prophylaxis, Surgical site infection, Ceftriaxone
|
| EOI:
|
-
|
| DOI:
|
-
|
| Download:
|
Request For Article
|
|
|