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Oral Leukoplakia Treatments: Past, Present and Future
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| Author:
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J.APARNA , D.EZHILARASAN, M.P. BRUNDHA
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| Abstract:
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Aim: Oral leukoplakia is the most common potentially malignant disorder affecting the oral cavity. The purpose of this article is to provide a literature review of the treatment methods and management of oral leukoplakia and therapies that may be preferred.
Materials and methods: The articles used in the present study were collected from search engines like core, semantic scholar, BASE, Mesh, ELSEVIER, PubMed, Google Scholar, Cochrane. The relevant articles were collected from the period of 2000 to 2020. It is a five-step process in the selection of articles – identification of clear objectives, identification of relevant articles, selection of data, data extraction, analysis and report about the management of different types of oral leukoplakia.
Results and discussion: Specific surgical and non-surgical therapies have been reported, but there is currently no general consensus on the most suitable treatment and on the span or period of follow-up of patients with this disorder. Treatment for oral leukoplakia will begin with removing risk factors (if there are any) such as tobacco abuse, betel chewing, alcohol abuse, candida infection with superimposed lesions, etc. Conservative therapy includes the use of chemopreventive agents such as vitamins (vitamins A, C, E), fenretinide (analogous to vitamin A), carotenoids (beta-carotene, lycopene), bleomycin, protease inhibitors, anti-inflammatory medications, green tea, Curcuma, and so on.
Conclusion: The main purpose of oral management of leukoplakia is to avoid malignant transformation or early detection of the lesion.
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| Keyword:
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Leukoplakia, Multiforms of OL, Management, Surgical, Non- surgical treatment
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.481
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| Download:
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Request For Article
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