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Molecular detection of Mycobacterium tuberculosis by IS 6110 in patients with pulmonary tuberculosis in Babylon Province-Iraq
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| Author:
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NAAM KADHIM HANI, AHMED ADIL ALI, AHMED HUSSEIN JASEM
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| Abstract:
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Insertion sequence (IS) 6110 is found at multiple sites in the Mycobacterium tuberculosis genome and displays a high degree of polymorphism with respect to copy number and insertion sites. Therefore, IS6110 is considered to be a useful molecular marker for diagnosis and strain typing of MTB. Tuberculosis, a communicable disease with significant morbidity and mortality, is the leading cause of the death in the world from bacterial infectious disease. Because of its public health importance, there is need for rapid and definitive method of detecting the causative organism. Several approaches have been attempted, but the molecular methods especially Polymerase Chain Reaction assays are the most promising for rapid detection of M. tuberculosis complex from clinical samples.
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| Keyword:
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Mycobacterium tuberculosis, Tuberculosis, polymerase chain reaction.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.464
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| Download:
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