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The frequency of Helicobacter pylori stool antigen in patients with different types of vitiligo in Iraqi Patients
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| Author:
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SANAA A. BDAIWI, MOHAMMED K. AL-HATTAB, MOHAMMED S. A. AL-NAFAKH
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| Abstract:
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Background A potential role of H. pylori infection in several extra-intestinal diseases including autoimmune and inflammatory skin diseases such as chronic urticaria, alopecia areata, psoriasis, and rosacea have been reported. Vitiligo is a common depigmenting skin disorder and autoimmunity has been suggested in the pathogenesis of vitiligo. There are few reports of association of H. pylori infection and vitiligo.
Aim of study The aim of our study is to evaluate the relationship between H. pylori infection and vitiligo.
Patients and methods The study group included 40 patients with vitiligo, and the control group included 40 age- and gender-matched individuals. H. pylori stool antigen test was performed in the patient and control groups to detect the presence of H. pylori infection.
Results H. pylori stool antigen test was positive in 22 (62.9%) of the patients and 13 (37.1%) of the controls. Statistically significant difference was found in H. pylori stool antigen test positivity between the patient and the control groups (P < 0.05). No significant relationship was found between H. pylori stool antigen test positivity and activity of vitiligo, family history, type, duration, and associated gastrointestinal symptoms of vitiligo. Conclusion The results indicate that H. pylori infection is increased in vitiligo patients, and may be necessary to screen vitiligo patients for H. pylori infection.
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| Keyword:
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Health; patients; infections; vitiligo
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.462
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| Download:
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