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Carbetocin Versus Oxytocin in Cesarean Section For Prevention of Primary Postpartum Hemorrhage
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| Author:
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MAY KHALIL ISMAIL, MAWAHIB ABID SALMAN, SHATHA AL SHARBATTI, RAJI SHARMA
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| Abstract:
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Background: Evidences are inconsistent for effectiveness of carbetocin compared to oxytocin in prevention of primary postpartum hemorrhage (PPH).
Objective: To compare the effectiveness and safety of carbetocin with oxytocin in prevention of PPH. Indicators of effectiveness were specified
Patients and methods: Prospective observational study was conducted at Thumbay Hospital, Ajman, UAE. That enrolled 286 women undergoing caesarean section who had received either Carbetocin (CG, n=168) or Oxytocin (OG, n= 118). The groups were compared for blood loss, required additional uterotonic agents, rate of blood transfusion and side-effects
Results: In CG vs OG there was significantly lower percentage of women required additional uterotonic agents (10.2 %vs 29.7%), significantly lower median intraoperative blood loss and significantly lower rate of blood transfusion. There were no significant differences in most of other side-effects
Conclusion: Carbetocin is more effective for prevention of PPH compared to oxytocin
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| Keyword:
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Carbetocin, oxytocin, cesarean section, postpartum hemorrhage
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.461
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| Download:
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