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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A study on the utilization of analgesics in post-operative patients

Author: VINOD K MATHEW, RAJIV KUMAR SAXENA , RAVIKUMAR K, SUSHEELA S, MAHESH N M, AKHIL SEBASTIAN, MAYISHA HALEEMA, RIHANA NAWABJAN
Abstract: Objective: Evaluation of the drug utilization pattern, therapeutic effect, and safety of analgesics among postoperative patients in a tertiary care teaching hospital, Bengaluru is the main objective of this study. Methods: A prospective observational cross-sectional study had been conducted for 6 months. Data were collected from the Departments of Orthopedics, Obstetrics, and Gynecology and Intensive Care Units, after getting approval from the Institutional Research and Ethics Committee and were analyzed by descriptive statistics. Most frequently prescribed analgesics with their pain-relieving effect and duration of sleep were assessed by utilizing the Rating Scale of Wong- Baker Faces and the Pain and Sleep Questionnaire three-item index. Results: We observed 158 post-operative patients, of which 42.4% (67) were male and 57.5 (91) were of the female gender. The average age of all the patients was between 18 and 80 years. Among all the analgesics (tramadol, paracetamol, and diclofenac) that were prescribed, intramuscular administration was the most preferred route. Diclofenac as alone and its combinations were found to be the frequently prescribed analgesic with a pain score of 82% as alone, and while in combination, it reduced the pain by 85% from its baseline value in postoperative patients. Correlating the sleep score with pain, it was found that there was a drastic increase in the sleep score of the patients as the pain had subsided. Conclusion: Thus, this study suggested that post-operative pain control was able to be achieved by no opioid drug diclofenac alone itself and opioid analogs had been added to patients for whom pain relief could not be achieved.
Keyword: Analgesics, Post-operative pain, Drug utilization prescribing pattern, Sleep score.
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