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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Analytical Study on Estimation of Mortality Assessment in Sepsis Patient in Intensive Care Unit

Author: RAMAKRISHNAN V, NAVEEN P, DR DONTHU RAJ KIRAN, DR. T. SAI SRAVANTHI
Abstract: Infectious diseases are the most leading Reason for horribleness Also mortal sin around overall. Those second heading reason for demise will be sepsis; septic stun is an life-undermining condition that expands those rate for hospitalization And mortal sin. Extreme sepsis might a chance to be sorted by vicinity of you quit offering on that one or more organ brokenness i. e. , metabolic acidosis, intense encephalopathy, oliguria, hypoxemia, coagulation or persistency hypotension. Will figure out the mortality of the patients for sepsis or extreme sepsis. can be done by using various scoring systems like GCS (Glasgow coma score), APACHE II and III, SOFA score. This can improve the patient care and also used for predicting the mortality of the sepsis or severe sepsis patients admitted in the ICU. It was a prospective observational study conducted for about 6 months. The study includes the patients with sepsis, severe sepsis and septic shock. The study excludes patients not with sepsis, pregnancy and lactating females. Data was collected from the ICU and analyzed by using SPPS software 20.0 for windows. Our study was aimed to estimate the mortality among adult patients admitted in the medical ICU with severe sepsis, sepsis. The total sample of 55 patients admitted to medical ICU and the mortality rate among them is 39%, and survival rate in them is 61%. The major co-morbidities observed in this study are a history of fever, diabetes mellitus, and respiratory co-morbitesis. Patients who are positive to sepsis or septic shock were having higher mean CRP (170.22+_129.01) when compared with survival group (131.88+_112.05). Hence, higher level of CRP indicated the high mortality rate. Present study showed 39% of mortality with increased CRP, serum lactate levels and body temperature are found to be clear predictors of mortality in sepsis, severe sepsis and septic shock by using SOFA score
Keyword: Sepsis, mortality risk assessment, SOFA score, Predictors of mortality.
DOI: https://doi.org/10.31838/ijpr/2020.SP1.473
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