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Simultaneous Assessment of Ebastine and Phenylephrine Hydrochloride Tablet form Dosage using Absorption Correction and Simultaneous Equation Techniques
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| Author:
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NAVEEN P, RAMAKRISHNAN V, DR. G. GANGA RAJU, DR K SUBBARAO
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| Abstract:
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A novel, accurate, simple, & sensitive UV - spectrophotometric ingestion rectification technique and concurrent condition strategy is produced for synchronous assurance of Phenylephrine & Ebastine HCL in bulk &in consolidated tablet dose structure. The methanol was utilized as solvent. The frequencies chose for assimilation correction strategy are 225 & 253 nm for Phenylephrine & Ebastine HCL individually and if there should arise an occurrence of concurrent condition technique the frequencies chose were 240 & 275 nm for Phenylephrine & Ebastine HCL correspondingly. The Beer's law complied with concentration extent of 4 – 40 µg/ml, for the two medications. The rate recuperation is discovered in extent of 100.51 - 101.40% for Phenylephrine HCL &100.42 - 101.27% for Ebastine. The established techniques were approved measurably and by recuperation examines. The % RSD value is discovered to be lower than 2. In this way, suggested strategies are precise, quick, easy, & economic might be effectively applied for synchronous assurance of Phenylephrine & Ebastine HCL in bulk and in joined tablet dose structure.
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| Keyword:
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Phenylephrine Hydrochloride estimation (PHE), UV spectrophotometric (UVS), EBS, PHE, simultaneous equation technique (SET), absorption correction technique (ACT)
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.471
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| Download:
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