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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A Potential Experimental Study on Clinical Profile and Outcomes of Organ Dysfunction amongst Sepsis Affected Role

Author: AQIB M, LALITHA R, DR. I. ANIL KUMAR, DR M. SUDHAKAR
Abstract: Sepsis is outlined as life-threatening organ dysfunction caused by a dysregulated host response to infection. It's become the foremost necessary explanation for Multiple Organ dysfunction Syndrome (MODS). The present study was an attempt to analyze the clinical characteristics of the sepsis patients, their symptoms, and the origin of infection, co-morbidities and outcomes of sepsis with organ dysfunction. It was a prospective observational study conducted for about 6 months. Data was collected from the ICU and analysed using SPSS software version20.0. In the present study a total of 51 cases were enrolled. Mean age of patients was 59.74 years. Male and females were 37and 14 respectively. Most common symptom was found as dyspnoea and fever. Cellulitis was found as the most common cause of infection with incidence rate of 32% followed by pneumonia 24%. All the cases some kind of organ dysfunction present among which respiratory, CVS and renal dysfunction were predominant. Diabetes mellitus was the most common comorbid condition in these cases. Sepsis is a vulnerable disease can affect any age group but it is found to be more mortal in elders with less significance value and more comorbidity. The overall mortality of sepsis was found to be29%.
Keyword: Sepsis, Organ dysfunction, Mortality rate, SOFA score.
DOI: https://doi.org/10.31838/ijpr/2020.SP1.469
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