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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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An Analytical Study of Ethanol Extraction of Myxopyrum Smilacifolium Blume And Pamburus Missionis

Author: VIJAYABHASKER V, AVINASH KULKARNI, MR RAVI KUMAR, DR BH RAVI VARMA
Abstract: Ethanolic concentrate of Myxopyrum smilacifolium Blume and Pamburus missionis Swingle are completed examined for hostile to ligament action by utilizing CFA prompted joint inflammation model. The investigation was completed for 28 days where the creatures are treated with 200 and 400 mg/kg ethanolic concentrate of leaves of Pamburus missionis and Myxopyrum smilacifolium subsequent to actuating joint inflammation in rodents by Freund's adjuvant. Further on 28th day the rodents are oppressed for the assessment of fiery boundaries like paw volume, paw thickness and Knee width. Blood was withdrawn from every creature of retro-orbital venous plexus of rodents and it is gathered into vial containing EDTA which is oppressed for biochemical boundaries. Treatment with ethanolic concentrate of Myxopyrum smilacifolium indicated huge (P<0.05) report at a portion of 400mg/kg body weight demonstrated generally intense and noteworthy action than Pamburus missionis and it is evidenced by analyzing the inflammatory parameter and biochemical parameters. Hereafter the present training exposed that ethanolic extract of Myxopyrum smilacifolium holds more prominent antiarthritic activity than Pamburus missionis.
Keyword: Pamburus missionis, Myxopyrum smilacifolium, anti-arthritic,Complete Freunds Adjuvant
DOI: https://doi.org/10.31838/ijpr/2020.SP2.430
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