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Immobile Females Receiving Medroxyprogesterone And Increased Risk Of Thrombosis
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| Author:
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ELHAM ALSHAMMARI
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| Abstract:
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The influence of contraceptives on the risk of thrombosis has been widely researched in the recent times. Thrombosis is a condition involving the development of a blood clot. Past scholarly work has indicated that thrombosis can occur because of extended periods of immobility, for instance when bedridden or during a hospital stay. Immobility affects the contraction of muscles, which are key in helping maintain the flow of blood through the veins, especially in the legs. The current review, therefore, sought to achieve three objectives. The first was to evaluate the link between immobilization and the risk of thrombosis. The outcome identified immobilization, bed rest and hospital stay as risk factors for deep vein thrombosis. The risk of thrombosis is increased further in the presence of comorbid factors, including age and surgery among many others. Secondly, the study examined the risk of thrombosis resulting from the use of medroxyprogesterone. Most of the reviewed studies showed a modest increase in VTE associated with the use of oral progestogens. Some of the studies also revealed that the risk of thrombosis increases in the presence of controlling factors, such as diabetes, factor V Leiden mutation, or smoking. Lastly, the review sought to provide recommendations on how to take care of bedridden females receiving medroxyprogesterone. In general, the findings showed that the risk of thrombosis can be minimized through mechanical and pharmacological approaches. Additionally, it was evident from the review that prophylaxis treatment has also been proposed as a suitable solution for taking care of immobile individuals with a high risk of thrombosis.
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| Keyword:
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females, immobility, medroxyprogesterone, risk, thrombosis.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP2.422
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| Download:
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Request For Article
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