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Inhibition of Calcium Oxalate Crystallization by the Fruit Extracts of Solanum xanthocarpum Schrad. & Wendl. and Pedalium murex Linn.
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UPLOADED BY-ADMIN, PARAS K.PATEL, NITESH NAYAK, HITESH PATEL, MANISH A. PATEL, MAHESH G. SARALAI, TEJAL R. GANDHI
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| Abstract:
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Urinary stones are one of the oldest and the most common afflictions in humans. This disease has tormented humans
since the earliest records of civilization. Ten percent of men and 3 % of women have a stone during their adult lives. Calcium
containing stones are the most common comprising about 75 % of all urinary calculi, which may be in the form of pure
calcium oxalate (50 %) or calcium phosphate (5 %) or a mixture of both (45 %). A number of plants have been mentioned in
the Indian ayurvedic system, which plays a vital role in the inhibition of kidney stones. In the present study, the inhibitory
potency of alcoholic and aqueous extracts of SolanumxanthocarpumSchrad. &Wendl.andPedalium murex Linn. fruitswere
evaluated on various stages of formation and on the growth of calcium oxalate crystals in vitro. A result obtained showed
that alcoholic extract of both plants has the higher capacity to inhibit the crystal formation and aggregation as compared to
their aqueous extracts. This effect may be because of the presence of saponin in the plant extract.
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| Keyword:
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Calcium oxalate, Pedalium murex, Solanumxanthocarpum, antiurolithiasis.
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