Impact Factor for Five Years is 1.55 (2012 - 2016). IJPRT Re-launched from 2017, for more details visit www.ijprtonline.com

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
Article In Press
ENZYMATIC AND NON ENZYMATIC ANTIOXIDANT ACTIVITY OF LEAF EXTRACTS OF AEGLE MARMELOS L. AND CENTELLA ASIATICA L.
ECO-FRIENDLY SYNTHESIS OF SILVER NANOPARTICLES USING AQUEOUS LEAVES EXTRACT OF CLOME GYNANDRA AND THEIR ANTIBACTERIAL ACTIVITY”
Synthesis, characterization, augmentation of iron oxide nanoparticles from Musa paradisaca peel extract and its antibacterial activity
Antianaphylactic Activity Polyherbal Formulation Against Systemic, Cutaneous And Compound 48/80 Induced Invitro Anaphylaxis
A study on an autoimmune disease-PSORIASIS
EFFICACY OF EMBLICA OFFICINALIS ON SERUM ENZYMES AGAINST AIR POLLUTANTS EXPOSED ALBINO RATS.
Formulation and Evaluation of Buccal Drug Delivery System of Ketorolac Tromethamine Using Mucoadhesive Polymers
Signaling pathways associated with liver cancer stem cell therapy
PHARMACOLOGICAL ACTIVITIES OF ASTAXANTHIN
A review on ethnobotany, phytochemistry and pharmacology of Plantago major L. – nature's treasure
12
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IJPRT ISSUE

January - March 6 [1] 2014

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Article Detail

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Pharmaceutical and chromatographical evaluation of dental gel containing bioactive: catechin

Author: DR. SUPRIYA JIRGE, TEJASVI P. CHALKE , ABHISHEK. D. DORLE , KRISHNA R. SHARMA , SUJIT K. NAGARE
Abstract: The present study deals with formulation of bioactive extract of leaves of Anacardium occidentale (cashew) into a dental gel and its evaluation. Dried, powdered bark was extracted with ethanol for 18 hours in a soxhlet apparatus. Catechin is one of the main constituent of the polyphenol of cashew leaves and same was further extracted from ethanol extract. Five dental gels containing catechin rich extract were formulated using various gelling agents. These gels were evaluated for physicochemical parameters, viscosity, spreadibility, extract content, dissolution, mucoadhesion, toxicity, in vitro permeation studies and antimicrobial activity. The selected gel was obtained as a brownish red colored lustrous gel having pH between 7.3-7.5 with a good spreadibility of 4-5secs and mucoadhesive force of 0.1gm. The content of catechin in the gel was 101.25% w/w by HPTLC method. The gel showed significantly good antimicrobial activity to that of ethanol extract and catechin rich extract. In dissolution studies the extract is released completely within 4 hours. In in-vitro permeation studies the entire extract is released within 6 hours. A dental gel was successfully formulated containing catechin rich extract of leaves of Anacardium occidentale.
Keyword: Anacardium occidentale, Catechin, Cashew, Dental gel, HPTLC
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Scopus (Elsevier)
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Ulrich's International Periodical Dictionary
Indian Science Abstract
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News & Events
Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)