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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
22nd NATIONAL CONVENTION

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Article In Press
Biomechanical/biochemical factors contributing to cardiac fibrosis in the heart and engineered cardiac tissue
THE ASSOCIATION AND LINKGAGE OF VARIOUS RETROVIRUSES AND ITS PROGRESSION TOWARDS NEURODEGENERATION
Architecture of Viral RNA Helicases; HCV helicase as Antiviral Target
GC-MS analysis of rhizome extract by Cold maceration of Curcuma amada Roxb.
Development and Evaluation of Febuxostat Sublingual Tablet Formulation
Development and Evaluation of Febuxostat Sublingual Tablet Formulation
A comparative study of adaptogenic effect of Withania somnifera with Mifepristone (a GR antagonist) on chronic stress - induced perturbations in glucose metabolism
In Vitro Anticancer Activity Of Leaves Of Rumex Vesicarius Linn And Symplocos Racemosa Roxb By Trypan Blue Method
PREPARATION AND INVITRO CHARACTERISATION OF ANTIBACTERIAL NANOCAPSULES
Cytotoxic potential of the crude solvent extract of Botryodiplodia theobromae – an endophytic fungi isolated from Catharanthus roseus.
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IJPRT ISSUE

January - March 6 [1] 2014

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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Article Detail

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Pharmaceutical and chromatographical evaluation of dental gel containing bioactive: catechin

Author: DR. SUPRIYA JIRGE, TEJASVI P. CHALKE , ABHISHEK. D. DORLE , KRISHNA R. SHARMA , SUJIT K. NAGARE
Abstract: The present study deals with formulation of bioactive extract of leaves of Anacardium occidentale (cashew) into a dental gel and its evaluation. Dried, powdered bark was extracted with ethanol for 18 hours in a soxhlet apparatus. Catechin is one of the main constituent of the polyphenol of cashew leaves and same was further extracted from ethanol extract. Five dental gels containing catechin rich extract were formulated using various gelling agents. These gels were evaluated for physicochemical parameters, viscosity, spreadibility, extract content, dissolution, mucoadhesion, toxicity, in vitro permeation studies and antimicrobial activity. The selected gel was obtained as a brownish red colored lustrous gel having pH between 7.3-7.5 with a good spreadibility of 4-5secs and mucoadhesive force of 0.1gm. The content of catechin in the gel was 101.25% w/w by HPTLC method. The gel showed significantly good antimicrobial activity to that of ethanol extract and catechin rich extract. In dissolution studies the extract is released completely within 4 hours. In in-vitro permeation studies the entire extract is released within 6 hours. A dental gel was successfully formulated containing catechin rich extract of leaves of Anacardium occidentale.
Keyword: Anacardium occidentale, Catechin, Cashew, Dental gel, HPTLC
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News & Events
22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit https://ncsp.ganpatuniversity.ac.in
Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)