IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Pharmaceutical and chromatographical evaluation of dental gel containing bioactive: catechin

Author: DR. SUPRIYA JIRGE, TEJASVI P. CHALKE , ABHISHEK. D. DORLE , KRISHNA R. SHARMA , SUJIT K. NAGARE
Abstract: The present study deals with formulation of bioactive extract of leaves of Anacardium occidentale (cashew) into a dental gel and its evaluation. Dried, powdered bark was extracted with ethanol for 18 hours in a soxhlet apparatus. Catechin is one of the main constituent of the polyphenol of cashew leaves and same was further extracted from ethanol extract. Five dental gels containing catechin rich extract were formulated using various gelling agents. These gels were evaluated for physicochemical parameters, viscosity, spreadibility, extract content, dissolution, mucoadhesion, toxicity, in vitro permeation studies and antimicrobial activity. The selected gel was obtained as a brownish red colored lustrous gel having pH between 7.3-7.5 with a good spreadibility of 4-5secs and mucoadhesive force of 0.1gm. The content of catechin in the gel was 101.25% w/w by HPTLC method. The gel showed significantly good antimicrobial activity to that of ethanol extract and catechin rich extract. In dissolution studies the extract is released completely within 4 hours. In in-vitro permeation studies the entire extract is released within 6 hours. A dental gel was successfully formulated containing catechin rich extract of leaves of Anacardium occidentale.
Keyword: Anacardium occidentale, Catechin, Cashew, Dental gel, HPTLC
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free