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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Synthesis, characterization and study biological activity of new Iron (III)complex with sulfadiazine derivative

Author: EHAB OBAID, NAJLAA J. HASANI, FARKED W. SALMAN, HYDER A. SHAHEED, ALI JABBAR RADHI
Abstract: Schiff base compound (L) was prepared by reaction 2-hydroxy-4-methoxybenzaldehyed and sulfadiazine in presence acid as catalyst. The preparation of Iron (III) complexfrom ferric chlorideand Schiff base ligand. Complex and ligand were confirmed by many methods included infrared spectral analysis, elemental analysis,13CNMR,1HNMR, mass spectroscopy, magnetic moment, molar conductance along with electronic. Octahedral configuration ironion has been proposed on the basis of magnetic andspectralstudies.Antibacterial activities of the synthesized compounds was screened against Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus.
Keyword: Sulfadiazine, imine, Antibacterial activities, reagent and complex
DOI: https://doi.org/10.31838/ijpr/2019.11.02.087
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