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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Antimicrobial activity of Allium sativum extract against some selected microorganism from different sources

Author: SHAIMAA MIZIL, SABA RIADKHUDHAIER, LIQAA JAMEEL IBRAHEEM, AHMED S. ALTAIE
Abstract: Qualitative phytochemical analysis indicate that garlic extract have many active compound with antimicrobial activity, we investigated the antimicrobial activity of aquous and alcohol extract of garlic(Aliumsativum)on some selected environmental and clinical isolates using agar well difussion method and the Minimum Inhibitary Concentration(MIC) was (25mg/ml),from the results we found that the environmental isolates(wild type)was more sensetive that the clinical one depending on the diameter of inhibition zone ,by comparing these results with the sensitivity to commercial antibiotics(Ampicillin, Tetracycline, Erythromycin, Vancomycine, Ciprodare, Gentamycin, Chloramphenicol, Rifampicin)we can observe that the environmental isolates were resist to(Erythromycin, Vancomycine, Ciprodare)meanwhile the clinical isolates were more resistance .after detection of the best garlic extract we found that the aquous extract more effective ,in the other hand this effect decrease by increasing PH of the extract.
Keyword: Allium sativumextract ; Antimicrobial activity; microorganism.
DOI: https://doi.org/10.31838/ijpr/2019.11.02.084
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