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Article Detail
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Evaluation of the Adiponectin Hormone and Lipid profile in patients with Hypothyroidism in Thi-Qar Province-Iraq
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| Author:
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HADEEL FARAJ
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| Abstract:
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There are 2 types of Hypothyroidism, primary hypothyroidism and secondary hypothyroidism. Primary
hypothyroidism arises when thyroid gland itself doesn’t work properly, whereas secondary hypothyroidism is initiated
when the thyroid gland doesn’t get adequate stimulation from thyroid stimulating hormones. Primary hypothyroidism
is triggered by iodine deficiency, autoimmune disease, radiation therapy, drugs or thyroid surgery The study was
designed to determine and compare the levels of TSH, T4, T3,adiponectin hormone (ADP) , and lipid profile
(TCH), (TG), (HDL), (LDL) , and (VLDL)in patients with Hypothyroidismand apparently healthy individuals.Blood
levelsTSH, T4, T3, adiponectin hormone (ADP), and lipid profile (TCH), (TG), (HDL), (LDL), and (VLDL) were
determined in 45patients with Hypothyroidismand 40 apparently healthy subjects.The levels of serum TSHand
biochemical markers of body lipid profile (serum TCH,TG,LDL,VLDL) were showing an enormous rise in patients
having Hypothyroidismwhen matched withthe control group. On the contrary, the levels of T4, T3,ADP, and
HDLindicated a considerable decrease in patients having Hypothyroidism when matched with control
subjects(P=0.05).In patients with Hypothyroidism, we foundan increase in TSH. There is a momentous elevation in
the cholesterol and triglyceride levels during patients with Hypothyroidism.Hypothyroidism can affect on lipoproteins
levels (high LDL, low HDL, and high VLDL., the decrease in T4,T3,and ADP can clearly occur.
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| Keyword:
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Hypothyroidism, primaryHypothyroidism, Adiponectin hormone, and lipid profile.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.02.078
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| Download:
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