IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

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0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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Role of IL -33 Levels with HCV Genotype in Predicting Chronic Liver Disease among Iraqi Patients

Author: EKHLAS FALIH, GHANIM HUSSEIN MAJEED, AHMED ABDUL -AL-HASSAN ABBAS
Abstract: Patients who suffers from hepatitis C chronic infection have different levels of hepatic inflammatory damage and fibrosis, with increasing risk for developing liver cirrhosis.IL-33 in liver disease has been attracted the attention of an increasing number of researchers due to its role in the development of a variety of liver diseases. This study aimed for examination of the potential role of IL-33 genotype with viral load in the pathogenicity of chronic liver disease among Iraqi patients. Current study included 40 healthy controls, 65 patients suffering from chronic hepatitis C infection, 15 patients with cirrhosis and 10 with hepato cellularcarcinoma who attended to the Gastroenterology and Hepatology Teaching Hospital in Baghdad during the period from June/2017 to February/2018.Human IL-33 estimated by ELISA technique. The genotype of Hepatitis C virus together with the viral load were detected by Real-TM PCR. The mean concentration of IL-33 in serum among patients with chronic hepatitis C(CHC)had significantly higher levels compared to the control group subjects (68.90pg./ml , VS17.19 pg./ml,respectively). Actually, with no significant differences found among patients groups (CHC, cirrhosis orhepato cellular carcinoma). Moreover, the most prevalence genotype in this study was genotype 4 then 1a.
Keyword: Hepatitis C virus, liver cirrhosis, HCC, interleukine-33genotype and HCV RNA
DOI: https://doi.org/10.31838/ijpr/2019.11.02.061
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Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477