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Analysis of Dose Calculation of Medicines Prescribed in Pediatric Age Group
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| Author:
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UPLOADED BY-ADMIN, ANKUR PATEL, BARNA GANGULY
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| Abstract:
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Weight-based dosing is needed for majority of drugs in pediatrics, that requires more accurate calculations than
for adults. This study was aimed to analyze the appropriateness of the dose of medicines prescribed to children
and comparison of the prescribed dose with that of standard dosing guidelines for pediatrics. Total 200 prescriptions
were included in the study (100 from out- patient department of pediatrics of Shri Krishna Hospital (SKH) and 100
from private (out patients only) pediatric clinic). Prescriptions which contain at least one of antibiotics, non-steroidal
anti-inflammatory drugs, cough treating agents or anti-histaminic drugs were included. Dose was calculated by using
dosing guidelines mentioned in the standard pediatric text-book or the rules frequently found in pediatric reference
textbooks and literature. The prescribed doses were compared to the standard doses (mg /kg/day). In our study
azithromycin and amoxicillin were commonly prescribed antibiotics and the prescribed doses were found to be same of
doses recommended by guidelines. For NSAIDs class, dose of paracetamol was found to be varying significantly in
both SKH and private clinic. In anti-histaminic class, the chorpheniramine maleate was prescribed maximally and
prescribed dose was found to be differing in SKH, but not in private clinic as compared to standard dose. Very
less cough treating preparations were prescribed in SKH in comparison to private pediatric clinic. Irrational prescribing
was found with cough treating agents and prescribed dose was found to be differing from accurate dose
for many of prescribed drugs.
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| Keyword:
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Antibiotics, anti-histaminics, cough treating agents, dose calculation, NSAIDs, pediatrics.
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| EOI:
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| DOI:
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