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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Analysis of Dose Calculation of Medicines Prescribed in Pediatric Age Group

Author: UPLOADED BY-ADMIN, ANKUR PATEL, BARNA GANGULY
Abstract: Weight-based dosing is needed for majority of drugs in pediatrics, that requires more accurate calculations than for adults. This study was aimed to analyze the appropriateness of the dose of medicines prescribed to children and comparison of the prescribed dose with that of standard dosing guidelines for pediatrics. Total 200 prescriptions were included in the study (100 from out- patient department of pediatrics of Shri Krishna Hospital (SKH) and 100 from private (out patients only) pediatric clinic). Prescriptions which contain at least one of antibiotics, non-steroidal anti-inflammatory drugs, cough treating agents or anti-histaminic drugs were included. Dose was calculated by using dosing guidelines mentioned in the standard pediatric text-book or the rules frequently found in pediatric reference textbooks and literature. The prescribed doses were compared to the standard doses (mg /kg/day). In our study azithromycin and amoxicillin were commonly prescribed antibiotics and the prescribed doses were found to be same of doses recommended by guidelines. For NSAIDs class, dose of paracetamol was found to be varying significantly in both SKH and private clinic. In anti-histaminic class, the chorpheniramine maleate was prescribed maximally and prescribed dose was found to be differing in SKH, but not in private clinic as compared to standard dose. Very less cough treating preparations were prescribed in SKH in comparison to private pediatric clinic. Irrational prescribing was found with cough treating agents and prescribed dose was found to be differing from accurate dose for many of prescribed drugs.
Keyword: Antibiotics, anti-histaminics, cough treating agents, dose calculation, NSAIDs, pediatrics.
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0.12
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