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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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CLINICAL EVALUATION OF BABOOL NEEM TOOTHPASTE IN ORAL HYGIENE AND DENTAL CARE

Author: RUCHI SRIVASTAVA, DR. ARUN GUPTA, DR. RAHUL BHOWATE, DR. RUCHI SRIVASTAVA, DR. SUNIL KUMAR, DR. S.V. DEVASTHALE, DR. J.L.N. SASTRY
Abstract: Context: A recent shift of preferences towards herbal ingredients is visible in oral care practices increasing the demand for commercially available oral care products containing natural ingredients. Babool Neem Toothpaste comprises extracts of herbs like Babool and Neem which have been used traditionally for oral care. The objective of the current clinical study was to investigate the efficacy of Babool Neem Toothpaste in oral hygiene and dental care. Methods: The study was conducted in patients of gingivitis & periodontitis and healthy subjects free from oral diseases. 30 subjects suffering from gingivitis and periodontitis were advised brushing with a neutral product for 1 week (washout period). Thereafter, they were randomized to receive either Babool Neem Toothpaste or Placebo Toothpaste for 12 weeks (Group 1). 20 healthy subjects free from oral diseases were similarly randomized to receive either Babool Neem Toothpaste or Placebo Toothpaste for 6 weeks (Group 2). Results were assessed on basis of changes in gingivitis in Group 1, and the microbiological assessments in group 2. Other parameters like the Lobene Stain and the Plaque indices and the organoleptic scorings were assessed in both the groups. Data was analyzed utilizing SAS, p value <0.05 was considered significant. Results & Conclusion: Babool Neem Toothpaste showed significant improvement in all the parameters assessed viz; gingivitis, dental stains, plaque, halitosis, microbial counts, the clinical attachment loss and global efficacy assessments, when compared to baseline. However, the similar results were also observed in Placebo Toothpaste Group
Keyword: Gingivitis, Periodontitis, Microbial assessment, Herbal Toothpaste, Oral care
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